Inosine Substitutions in RNA Activate Latent G-Quadruplexes.
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DOI: 10.1021/jacs.1c05214
Abstract: It is well-accepted that gene expression is heavily influenced by RNA structure. For instance, stem-loops and G-quadruplexes (rG4s) are dynamic motifs in mRNAs that influence gene expression. Adenosine-to-inosine (A-to-I) editing is a common chemical modification… read more here.
Keywords: substitutions rna; inosine substitutions; gene expression; inosine ... See more keywords