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Published in 2018 at "Cancer Immunology Research"
DOI: 10.1158/2326-6066.cir-17-0716
Abstract: Tumor-derived microparticles activate a lysosomal pathway enabling dendritic cell upregulation of costimulatory molecules and presentation of tumor antigens to CD+ T cells. Elucidation of this molecular pathway has clinical implications for the development of improved…
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Keywords:
activate lysosomal;
tumor antigen;
cd8 cells;
mechanisms dendritic ... See more keywords