trans-δ-Viniferin inhibits Ca2+-activated Cl- channels and improves diarrhea symptoms.
Sign Up to like & getrecommendations! Published in 2019 at "Fitoterapia"
DOI: 10.1016/j.fitote.2019.104367
Abstract: Ca2+-activated Cl- channels (CaCCs) wildly exist in many tissues which play an important role in ion transport and excitation conduction, especially fluid secretion and smooth muscle contraction in epithelial tissues. TMEM16A as a classic CaCC… read more here.
Keywords: tvn; ca2 activated; diarrhea; viniferin inhibits ... See more keywords
A potent and selective activator of large‐conductance Ca2+‐activated K+ channels induces preservation of mitochondrial function after hypoxia and reoxygenation by handling of calcium and transmembrane potential
Sign Up to like & getrecommendations! Published in 2024 at "Acta Physiologica"
DOI: 10.1111/apha.14151
Abstract: Ischaemic heart disease remains a significant cause of mortality globally. A pharmacological agent that protects cardiac mitochondria against oxygen deprivation injuries is welcome in therapy against acute myocardial infarction. Here, we evaluate the effect of… read more here.
Keywords: hypoxia reoxygenation; large conductance; ca2 activated; activated channels ... See more keywords
Abstract 4140803: Vasomotion in human arteries and its ion channelbased on regulations: 10 years study
Sign Up to like & getrecommendations! Published in 2024 at "Circulation"
DOI: 10.1161/circ.150.suppl_1.4140803
Abstract: Vasomotion is the oscillation of vascular tone which gives rise to flow motion of blood into an organ. As is well known, spontaneous contractile organs such as heart, GI, and genitourinary tract produce rhythmic contraction.… read more here.
Keywords: vasomotion human; 4140803 vasomotion; human arteries; activated channels ... See more keywords
Role of stretch-activated channels in light-generated action potentials mediated by an intramembrane molecular photoswitch
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DOI: 10.1186/s12967-024-05902-4
Abstract: The use of light to control the activity of living cells is a promising approach in cardiac research due to its unparalleled spatio-temporal selectivity and minimal invasiveness. Ziapin2, a newly synthesized azobenzene compound, has recently… read more here.
Keywords: role stretch; generated action; stretch activated; light generated ... See more keywords