Hypoxia Activated Fluorescent Probe Based on Self-immolative Block Copolymer.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202100417
Abstract: This work reported a hypoxia activated fluorescent probe for tumor imaging by using self-immolative block copolymer with azobenzene linkage. The water-soluble polymer composed of self-immolative building blocks showed no obvious fluorescence. Under the hypoxic microenvironment… read more here.
Keywords: activated fluorescent; block copolymer; immolative block; fluorescent probe ... See more keywords
A pH-activated fluorescent probe via transformation of azo and hydrazone forms for lysosomal pH imaging.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc03999k
Abstract: We developed a fluorescent probe Sth-NH by introducing a 6-hydroxypyridone skeleton. The presence of an active proton enables the probe to transform from a deprotonated azo form to a hydrazone form in a strongly acidic… read more here.
Keywords: probe via; activated fluorescent; via transformation; fluorescent probe ... See more keywords
A malondialdehyde-activated fluorescent probe reveals lysosomal dysfunction in atherosclerosis
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DOI: 10.1039/d5sc04487a
Abstract: Lysosomes, serving as the digestive centers in cells, play a crucial role in lipid metabolism, inflammatory regulation, and cellular homeostasis. The bidirectional vicious cycle between lysosomal dysfunction and oxidative stress synergistically promotes the occurrence, development… read more here.
Keywords: atherosclerosis; activated fluorescent; malondialdehyde activated; lysosomal dysfunction ... See more keywords