METTL3/METTL14 Transactivation and m6A-Dependent TGF-β1 Translation in Activated Kupffer Cells
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DOI: 10.1016/j.jcmgh.2021.05.007
Abstract: Background and Aims Transforming growth factor β1 (TGF-β1) secreted from activated Kupffer cells (KC) promotes the progression of nonalcoholic steatohepatitis (NASH) to liver fibrosis. N6-methyladenosine (m6A) RNA modification participates in various cell stress responses, yet… read more here.
Keywords: tgf; mettl3 mettl14; m6a; activated kupffer ... See more keywords