LAUSR

Development of Light‐Activated LXR Agonists

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2 Published in 2023 at "ChemMedChem"

DOI: 10.1002/cmdc.202200647

Abstract: Activation of the oxysterol‐sensing transcription factor liver X receptor (LXR) has been studied as a therapeutic strategy in metabolic diseases and cancer but is compromised by the side effects of LXR agonists. Local LXR activation… read more here.

Keywords: cancer; lxr agonists; activated lxr; development light ... See more keywords

Inhibition of Human Cytomegalovirus Particle Maturation by Activation of Liver X Receptor

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1 Published in 2022 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2022.846386

Abstract: Human cytomegalovirus (HCMV), a herpesvirus family member, is a large, complex enveloped virus. The activation of liver X receptor (LXR) can significantly inhibit the replication of HCMV and weaken the virulence of progeny virus (unpublished… read more here.

Keywords: maturation; hcmv; human cytomegalovirus; activated lxr ... See more keywords