Paradoxical imbalance between activated lymphocyte protein synthesis capacity and rapid division rate
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DOI: 10.7554/elife.89015
Abstract: Rapid lymphocyte cell division places enormous demands on the protein synthesis machinery. Flow cytometric measurement of puromycylated ribosome-associated nascent chains after treating cells or mice with translation initiation inhibitors reveals that ribosomes in resting lymphocytes… read more here.
Keywords: lymphocyte protein; protein; activated lymphocyte; division ... See more keywords