A DARPin targeting activated Mac-1 is a novel diagnostic tool and potential anti-inflammatory agent in myocarditis, sepsis and myocardial infarction
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DOI: 10.1007/s00395-021-00849-9
Abstract: The monocyte β 2 -integrin Mac-1 is crucial for leukocyte–endothelium interaction, rendering it an attractive therapeutic target for acute and chronic inflammation. Using phage display, a Designed-Ankyrin-Repeat-Protein (DARPin) was selected as a novel binding protein… read more here.
Keywords: darpin; anti inflammatory; myocardial infarction; mac ... See more keywords