A CTNNB1‐altered medulloblastoma shows the immunophenotypic, DNA methylation and transcriptomic profiles of SHH‐activated, and not WNT‐activated, medulloblastoma
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DOI: 10.1111/nan.12815
Abstract: Recent advancements in molecular characterisation have identified four principal molecular groups of medulloblastoma: WNT, SHH, group 3 and group 4. Each has its characteristic clinical features, signature genetic alterations and distinct DNA methylome profiles. Thus… read more here.
Keywords: wnt activated; activated medulloblastoma; dna methylation; medulloblastoma ... See more keywords