Basic coagulation tests as surrogates of dabigatran levels in a pre-operative setting: Analysis of five activated partial thromboplastin time reagents and thrombin time.
Sign Up to like & getrecommendations! Published in 2018 at "Thrombosis research"
DOI: 10.1016/j.thromres.2018.09.051
Abstract: BACKGROUND In patients who are receiving dabigatran, a direct oral anticoagulant, measuring the anticoagulant effect before surgery may be needed in certain circumstances. Although the dilute thrombin time (dTT) can reliably measure dabigatran levels, it… read more here.
Keywords: coagulation tests; time; thrombin time; activated partial ... See more keywords
SUBSEQUENT CHANGES IN DOSING REQUIREMENTS TO PRODUCE THERAPEUTIC ANTICOAGULATION WITH INJECTABLE DIRECT THROMBIN INHIBITORS AFTER INSTITUTIONAL CHANGE TO THE ACTIVATED PARTIAL THROMBOPLASTIN TIME REAGENT
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(18)32645-7
Abstract: Injectable direct thrombin inhibitors (iDTI) argatroban and bivalirudin are useful in the management of patients with documented or suspected heparin induced thrombocytopenia (HIT). Management of iDTIs includes monitoring with the activated partial thromboplastin time (aPTT)… read more here.
Keywords: thromboplastin time; direct thrombin; injectable direct; thrombin inhibitors ... See more keywords
An Analysis of the Sensitivity of the Activated Partial Thromboplastin Time (APTT) Assay, as Used in a Large Laboratory Network, to Coagulation Factor Deficiencies.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of clinical pathology"
DOI: 10.1093/ajcp/aqac013
Abstract: OBJECTIVES To advance knowledge in using the ex vivo method to identify factor sensitivity of the activated partial thromboplastin time (APTT), using data from a hemophilia and reference hemostasis laboratory; to evaluate application of inclusion… read more here.
Keywords: laboratory; sensitivity; activated partial; partial thromboplastin ... See more keywords
Low-Dose Versus Therapeutic Anticoagulation in Patients on Extracorporeal Membrane Oxygenation: A Pilot Randomized Trial.
Sign Up to like & getrecommendations! Published in 2019 at "Critical Care Medicine"
DOI: 10.1097/ccm.0000000000003780
Abstract: OBJECTIVES To determine whether randomization of patients undergoing extracorporeal membrane oxygenation to either therapeutic or a low-dose anticoagulation protocol results in a difference in activated partial thromboplastin time and anti-Xa. DESIGN Randomized, controlled, unblinded study.… read more here.
Keywords: activated partial; anticoagulation; extracorporeal membrane; membrane oxygenation ... See more keywords
Activated Partial Thromboplastin Time versus Anti-Factor Xa Levels for Monitoring Unfractionated Heparin Therapy in Children: An Institutional Experience
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000000966
Abstract: To the Editor: Epidemiologic studies from Canada and the Netherlands estimated the incidence of venous thrombo-embolism (VTE) to be 0.07 to 0.14/10,000 children (and neonates), respectively.1,2 A recent study, however, has indicated a 70% increase… read more here.
Keywords: heparin; thromboplastin time; partial thromboplastin; unfractionated heparin ... See more keywords
Prolonged activated partial thromboplastin time predicts poor short‐term prognosis in patients with acute pancreatitis: A retrospective cohort study
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Science"
DOI: 10.1111/cts.13378
Abstract: It is unclear whether activated partial thromboplastin time (APTT) is predictive of survival in patients with acute pancreatitis (AP). Our study aimed to investigate the relationship between APTT and short‐term prognosis in AP. From the… read more here.
Keywords: activated partial; group; cohort; study ... See more keywords
Unexpected, isolated activated partial thromboplastin time prolongation: A practical mini‐review
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Haematology"
DOI: 10.1111/ejh.13394
Abstract: A common inquiry in coagulation laboratories is how to interpret an unexpected, isolated prolonged activated partial thromboplastin time (APTT). In this context, isolated means together with a normal prothrombin time (PT) and/or normal international normalized… read more here.
Keywords: thromboplastin time; time; isolated prolonged; partial thromboplastin ... See more keywords
Effect of dual versus mono antiplatelet therapy on recurrent stroke modulated by activated partial thromboplastin time
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Neurology"
DOI: 10.1111/ene.13961
Abstract: The efficacy of dual antiplatelet treatment may be modified by many factors. The aim was to assess whether the effect of clopidogrel plus aspirin versus aspirin alone on recurrent stroke would be affected by admission… read more here.
Keywords: thromboplastin time; antiplatelet; recurrent stroke; effect ... See more keywords
Why does activated partial thromboplastin time prolongation occur in severe fever with thrombocytopenia syndrome?
Sign Up to like & getrecommendations! Published in 2020 at "BMJ Case Reports"
DOI: 10.1136/bcr-2020-235447
Abstract: Severe fever with thrombocytopenia syndrome (SFTS) is caused by infection with SFTS virus and this mortality rate is 16.2% to 30%. An 85-year-old male patient presented to the emergency department of the hospital with primary… read more here.
Keywords: severe fever; thrombocytopenia syndrome; time; fever thrombocytopenia ... See more keywords
Activated Partial Thromboplastin Time and Mortality in Coronary Artery Bypass Grafting Patients
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/2918654
Abstract: Background To evaluate the prognostic value of preoperative activated partial thromboplastin time (APTT) in patients who underwent coronary artery bypass grafting (CABG). Methods All data were extracted from the Medical Information Mart for Intensive Care… read more here.
Keywords: thromboplastin time; year; activated partial; partial thromboplastin ... See more keywords
The missing slope: paradoxical shortening of activated partial thromboplastin time in a patient on unfractionated heparin therapy
Sign Up to like & getrecommendations! Published in 2021 at "Biochemia Medica"
DOI: 10.11613/bm.2021.021003
Abstract: This case report describes false shortening of activated partial thromboplastin time (aPTT) due to erroneous optical reading of the clotting point in the presence of unfractionated heparin (UFH), and a biphasic waveform. Activated partial thromboplastin… read more here.
Keywords: therapy; time; partial thromboplastin; activated partial ... See more keywords