Abstract 5159: Characterization of a novel class of RAS inhibitory compounds with potent anti-tumor activity
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-5159
Abstract: Introduction: Over 30% of all human cancers harbor activating RAS mutations which induce deregulation of the cell cycle, uncontrolled proliferation, and decreased apoptosis. Through a phenotypic screening strategy, we have identified a series of indene… read more here.
Keywords: growth; dc070 547; activated ras; cell ... See more keywords