Structure of the human activated spliceosome in three conformational states.
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DOI: 10.2210/pdb5z58/pdb
Abstract: During each cycle of pre-mRNA splicing, the pre-catalytic spliceosome (B complex) is converted into the activated spliceosome (Bact complex), which has a well-formed active site but cannot proceed to the branching reaction. Here, we present… read more here.
Keywords: conformational states; bact complex; activated spliceosome; structure ... See more keywords