Bioorthogonal chemistry and illumination controlled programmed size-changeable nanomedicine for synergistic photodynamic and hypoxia-activated therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2022.121480
Abstract: Photodynamic therapy (PDT) can aggravate the hypoxia aggravation and be further utilized for the activation of hypoxia-activated prodrug (HAP). Ideally, photosensitizers (PSs) are mainly administrated to tumor vasculatures adjacent to regions with high oxygen to… read more here.
Keywords: hypoxia; hypoxia activated; hap; tumor ... See more keywords
Induced-volatolomics for the design of tumour activated therapy
Sign Up to like & getrecommendations! Published in 2023 at "Chemical Science"
DOI: 10.1039/d2sc06797h
Abstract: The discovery of tumour-associated markers is of major interest for the development of selective cancer chemotherapy. Within this framework, we introduced the concept of induced-volatolomics enabling to monitor simultaneously the dysregulation of several tumour-associated enzymes… read more here.
Keywords: volatolomics design; tumour activated; activated therapy; therapy ... See more keywords