Lysosomal Adenosine Triphosphate-Activated Upconversion Nanoparticle/Carbon Dot Composite for Ratiometric Imaging of Hepatotoxicity.
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DOI: 10.1021/acs.analchem.2c03351
Abstract: Drug-induced hepatotoxicity (DIH) is a common cause of acute liver injury, endangering human health. Intracellular adenosine triphosphate (ATP) content in hepatocytes is related to hepatotoxicity. Thus, monitoring the dynamic changes in lysosomal ATP is promising… read more here.
Keywords: activated upconversion; dih; ratiometric imaging; hepatotoxicity ... See more keywords