Relaxin activates AMPK-AKT signaling and increases glucose uptake by cultured cardiomyocytes
Sign Up to like & getrecommendations! Published in 2018 at "Endocrine"
DOI: 10.1007/s12020-018-1534-3
Abstract: PurposeMany evidences show that the hormone relaxin plays a pivotal role in the physiology and pathology of the cardiovascular system. This pleiotropic hormone exerts regulatory functions through specific receptors in cardiovascular tissues: in experimental animal… read more here.
Keywords: cardiomyocytes relaxin; glucose uptake; activates ampk; relaxin ... See more keywords
PF-06409577 Activates AMPK Signaling and Inhibits Osteosarcoma Cell Growth
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DOI: 10.3389/fonc.2021.659181
Abstract: Osteosarcoma (OS) is a common primary bone malignancy. We here investigated the potential activity of PF-06409577, a novel, potent, and direct activator of AMP-activated protein kinase (AMPK), against human OS cells. In established (U2OS, MG-63,… read more here.
Keywords: cell growth; activates ampk; activation; 06409577 activates ... See more keywords
Lactate Activates AMPK Remodeling of the Cellular Metabolic Profile and Promotes the Proliferation and Differentiation of C2C12 Myoblasts
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DOI: 10.3390/ijms232213996
Abstract: Lactate is a general compound fuel serving as the fulcrum of metabolism, which is produced from glycolysis and shuttles between different cells, tissues and organs. Lactate is usually accumulated abundantly in muscles during exercise. It… read more here.
Keywords: cellular metabolic; activates ampk; remodeling cellular; differentiation ... See more keywords