IGFBP5 modulates lipid metabolism and insulin sensitivity through activating AMPK pathway in non-alcoholic fatty liver disease.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117997
Abstract: AIMS Non-alcoholic fatty liver disease (NAFLD) characterized by excessive hepatic fat deposition is an increasing public health issue worldwide. Insulin resistance is a pivotal factor in NAFLD progression. Studies have found that IGFBP5 was related… read more here.
Keywords: insulin; activating ampk; non alcoholic; igfbp5 ... See more keywords
Crataegus aronia prevents high-fat diet-induced hepatic steatosis in rats by activating AMPK-induced suppression of SREBP1 and activation of PPARĪ±.
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DOI: 10.1111/jfbc.13945
Abstract: This study examined if the aqueous extract of Crataegus aronia (C. aronia) can prevent high-fat diet (HFD)-induced hepatic steatosis in rats by activating AMPK. Adult male Wistar rats were fed either a control diet or… read more here.
Keywords: hepatic steatosis; activating ampk; crataegus aronia; aronia ... See more keywords
Zingerone ameliorates non-alcoholic fatty liver disease in rats by activating AMPK.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.14149
Abstract: This study was conducted to test the protective potential of Zingerone against a high-fat diet (HFD)-mediated non-alcoholic fatty liver disease (NAFLD) development in rats and examined in this protection is mediated modulating AMP-activated protein kinase… read more here.
Keywords: alcoholic fatty; zingerone; non alcoholic; activating ampk ... See more keywords
Eye Drops of Metformin Prevents Fibrosis After Glaucoma Filtration Surgery in Rats via Activating AMPK/Nrf2 Signaling Pathway
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DOI: 10.3389/fphar.2020.01038
Abstract: Metformin has effective therapeutic effects in anti-tumor and anti-fibrotic diseases. However, how the antifibrotic effect of metformin in the eye and how it is transferred are still unclear. Here, the eye drop of metformin treatment… read more here.
Keywords: via activating; surgery; fibrosis; activating ampk ... See more keywords
Atractylenolide III inhibits epithelial-mesenchymal transition in small intestine epithelial cells by activating the AMPK signaling pathway
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DOI: 10.3892/mmr.2022.12614
Abstract: Compared with the available drugs for the treatment of fibrosis in other organs, the development of intestinal anti-fibrosis drugs is limited. Therefore, it is of practical significance to examine novel drugs to delay or block… read more here.
Keywords: mesenchymal transition; atl iii; atractylenolide iii; iii ... See more keywords