Metformin reduces proteinuria in spontaneously hypertensive rats by activating the HIF-2α-VEGF-A pathway.
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DOI: 10.1016/j.ejphar.2020.173731
Abstract: Metformin has protective effects on diabetic nephropathy. However, the mechanism underlying the renoprotective action of metformin in spontaneously hypertensive rats (SHR) is not completely understood. We determined the role of metformin in proteinuria and investigated… read more here.
Keywords: spontaneously hypertensive; hypertensive rats; metformin; rat ... See more keywords