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Published in 2018 at "Reproductive Medicine and Biology"
DOI: 10.1002/rmb2.12094
Abstract: Pituitary adenylate cyclase‐activating polypeptide (PACAP) is a multifunctional peptide that is isolated and identified from the ovine hypothalamus, whose effects and mechanisms have been elucidated in numerous studies. The PACAP and its receptor are widely…
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Keywords:
activating polypeptide;
cyclase activating;
pituitary adenylate;
adenylate cyclase ... See more keywords
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Published in 2018 at "Neurotoxicology"
DOI: 10.1016/j.neuro.2018.03.010
Abstract: HighlightsPACAP has very potent neuroprotective actions against different neurotoxic agents.We give a summary of the neuroprotective effects against the most commonly used neurotoxic agents, such as 6‐OHDA, MPTP, glutamate and some less well‐known neurotoxic compounds.…
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Keywords:
cyclase activating;
neuroprotective effects;
neurotoxic agents;
pituitary adenylate ... See more keywords
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Published in 2017 at "Pharmacological Research"
DOI: 10.1016/j.phrs.2016.12.025
Abstract: Graphical abstract Figure. No Caption available. Abstract The pituitary adenylate cyclase‐activating polypeptide (PACAP)‐27 modulates various biological processes, from the cellular level to function specification. However, the cardiac actions of this neuropeptide are still under intense…
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Keywords:
cyclase activating;
bpm;
pacap;
pituitary adenylate ... See more keywords
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Published in 2021 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2021.663418
Abstract: Pituitary adenylate cyclase-activating polypeptide (PACAP) is a highly conserved neuropeptide that regulates neuronal physiology and transcription through Gs/Gq-coupled receptors. Its actions within hypothalamic, limbic, and mnemonic systems underlie its roles in stress regulation, affective processing,…
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Keywords:
cyclase activating;
pacap;
pituitary adenylate;
adenylate cyclase ... See more keywords
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Published in 2020 at "International Journal of Molecular Medicine"
DOI: 10.3892/ijmm.2020.4808
Abstract: Endothelial monocyte-activating polypeptide II (EMAP II) is a sensitive marker of neurotoxic injury, the expression of which increases significantly under conditions of stress, such as hypoxia or apoptosis. Studies have confirmed the extensive apoptosis of…
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Keywords:
hippocampus;
group;
activating polypeptide;
expression ... See more keywords