Inhibition of ferroptosis-related NCF2 blocks the progression of lupus nephritis by activating PPARα pathway
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DOI: 10.1186/s41065-025-00547-9
Abstract: Ferroptosis is involved in the pathogenesis of Lupus nephritis (LN), but its mechanism of action in LN remains unknown. This study aims to explore the effect of the ferroptositic-related gene neutrophil cytosolic factor 2 (NCF2)… read more here.
Keywords: ferroptosis related; activating ppar; lupus nephritis; ferroptosis ... See more keywords
Qing-Luo-Yin Eases T Cells-Mediated Angiogenesis in Adjuvant-Induced Arthritis Rats by Activating PPARγ
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DOI: 10.2147/jir.s508316
Abstract: Introduction Qing-Luo-Yin (QLY) is an anti-rheumatic herbal formula potentially activating PPARγ. The study investigated if and how this property contributes to its anti-angiogenesis effects. Methods Adjuvant-induced arthritis (AIA) rats were orally treated by QLY or… read more here.
Keywords: luo yin; ppar; activating ppar; qing luo ... See more keywords
Activating PPARβ/δ Protects against Endoplasmic Reticulum Stress-Induced Astrocytic Apoptosis via UCP2-Dependent Mitophagy in Depressive Model
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DOI: 10.3390/ijms231810822
Abstract: Abstracts As energy metabolism regulation factor, peroxisome proliferator-activated receptor (PPAR) is thought to be a potential target for the treatment of depression. The present study was performed to evaluate the effects of activating PPARβ/δ, the… read more here.
Keywords: endoplasmic reticulum; stress; apoptosis; reticulum stress ... See more keywords