Prediction of Fluorophore Brightness in Designed Mini Fluorescence Activating Proteins.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of chemical theory and computation"
DOI: 10.1021/acs.jctc.1c00748
Abstract: The de novo computational design of proteins with predefined three-dimensional structure is becoming much more routine due to advancements both in force fields and algorithms. However, creating designs with functions beyond folding is more challenging.… read more here.
Keywords: prediction fluorophore; fluorescence activating; activating proteins; mini fluorescence ... See more keywords
Ras GTPase-activating proteins control neuronal circuit development in barrel cortex layer 4
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.901774
Abstract: The cerebral cortex comprises a complex and exquisite network of neuronal circuits that is formed during development. To explore the molecular mechanisms involved in cortical circuit formation, the tactile somatosensory pathway that connects the whiskers… read more here.
Keywords: ras gtpase; activating proteins; circuit; gtpase activating ... See more keywords
Role of IQ Motif-Containing GTPase-Activating Proteins in Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.920652
Abstract: IQ motif-containing GTPase-activating proteins (IQGAPs) are a class of scaffolding proteins, including IQGAP1, IQGAP2, and IQGAP3, which govern multiple cellular activities by facilitating cytoskeletal remodeling and cellular signal transduction. The role of IQGAPs in cancer… read more here.
Keywords: hepatocellular carcinoma; activating proteins; role; motif containing ... See more keywords