Complement activation by AAV-neutralizing antibody complexes.
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DOI: 10.1089/hum.2023.018
Abstract: Treatment of monogenetic disorders using adeno-associated viral vectors (AAV) is an area of intense interest. AAV is a human pathogen and pre-existing capsid antibodies are prevalent in the population posing a challenge to safety and… read more here.
Keywords: aav neutralizing; complement activation; antibody complexes; neutralizing antibody ... See more keywords