Defective respiration and one-carbon metabolism contribute to impaired naïve T cell activation in aged mice
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DOI: 10.1073/pnas.1804149115
Abstract: Significance T cell-mediated immune responses are compromised in aged individuals, leading to increased morbidity and reduced response to vaccination. Finding new ways to boost T cell immunity in the elderly is key for enhancing their… read more here.
Keywords: activation aged; metabolism; aged cells; cell activation ... See more keywords