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Published in 2020 at "Molecular immunology"
DOI: 10.1016/j.molimm.2020.09.020
Abstract: The aims of the present study were to investigate the signaling mechanisms for sphingosine-1-phosphate (S1P)-induced airway smooth muscle cells (ASMCs) proliferation and to explore the effect of activation of adenosine monophosphate-activated protein kinase (AMPK) on…
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Keywords:
activation ampk;
s1p induced;
activation;
asmcs proliferation ... See more keywords
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Published in 2020 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2020.134762
Abstract: Rab11, a small GTPase, is an important protein in the regulation of intracellular plasma membrane trafficking. Schwann cells are the main cells of peripheral nerves and knockdown of Rab11 in these cells inhibits the formation…
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Keywords:
glut1 glut3;
cell proliferation;
activation ampk;
cell ... See more keywords
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Published in 2017 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2016.12.019
Abstract: Abstract Emerging evidence has shown that berberine has a protective effect against metabolic syndrome such as obesity and type II diabetes mellitus by activating AMP‐activated protein kinase (AMPK). AMPK induces CD36 trafficking to the sarcolemma…
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Keywords:
lipid accumulation;
activation ampk;
fatty acid;
cd36 ... See more keywords
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Published in 2022 at "Renal Failure"
DOI: 10.1080/0886022x.2022.2126789
Abstract: Abstract Background The pathogenesis of peritoneal dialysis (PD)-related peritoneal fibrosis (PF) is not clearly understood, and current treatment options are limited. Methods In this study, the effect of PD-related PF on mitochondrial biogenesis was investigated,…
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Keywords:
mitochondrial biogenesis;
ampk pgc;
pgc pathway;
activation ampk ... See more keywords
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Published in 2018 at "Human Molecular Genetics"
DOI: 10.1093/hmg/ddy245
Abstract: Myotonic dystrophy type 1 (DM1) is a debilitating multisystemic disorder caused by a triplet repeat expansion in the 3' untranslated region of dystrophia myotonica protein kinase mRNAs. Mutant mRNAs accumulate in the nucleus of affected…
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Keywords:
dm1 mouse;
ampk;
activation ampk;
dm1 ... See more keywords
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Published in 2017 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.13046
Abstract: Although our recent study has demonstrated that mitotic spindle assembly checkpoint protein (MAD2B) mediates high glucose‐induced neuronal apoptosis, the mechanisms for MAD2B degradation under hyperglycaemia have not yet been elucidated. In this study, we first…
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Keywords:
degradation;
mad2b;
activation ampk;
high glucose ... See more keywords
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Published in 2019 at "Oral diseases"
DOI: 10.1111/odi.13212
Abstract: OBJECTIVE To investigate the effect of AMPK on tight junction (TJ) components, ZO-1 and F-actin, and the underlying mechanisms of AMPK in inhibiting migration of tongue squamous cell carcinoma (TSCC) cells. METHODS Expression and distribution…
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Keywords:
migration;
activation ampk;
activation;
tscc cells ... See more keywords
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Published in 2018 at "Journal of Vascular Research"
DOI: 10.1159/000489959
Abstract: Background: Aging, obesity, and diabetes favor vascular dysfunction. Endothelial activation of adenosine monophosphate-activated protein kinase (AMPK) has protective effects in diabetes. Methods: Mice with constitutive endothelial activation of AMPK (CA-AMPK) were given a high fat…
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Keywords:
activation ampk;
weight loss;
renal arteries;
activation ... See more keywords
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1
Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.22055
Abstract: The present study tested the potential effect of OSU53, a novel AMPK activator, against hydrogen peroxide (H2O2)-induced spinal cord neuron damages. Treatment with OSU53 attenuated H2O2-induced death and apoptosis of primary murine spinal cord neurons.…
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Keywords:
osu53;
cord;
activation ampk;
cord neurons ... See more keywords