Activation of canonical BMP4-SMAD7 signaling suppresses breast cancer metastasis.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer research"
DOI: 10.1158/0008-5472.can-19-0743
Abstract: Metastasis is the major cause of death in cancer patients; with no therapeutic cure, treatments remain largely palliative. As such, new targets and therapeutic strategies are urgently required. Here we show that bone morphogenetic protein-4… read more here.
Keywords: metastasis; smad7; cancer; breast cancer ... See more keywords
Lower expression of PDZRN3 induces endometrial carcinoma progression via the activation of canonical Wnt signaling.
Sign Up to like & getrecommendations! Published in 2022 at "Oncology letters"
DOI: 10.3892/ol.2022.13218
Abstract: Endometrial carcinoma (EC) exhibits an extremely malignant biological behavior and has a high mortality rate. EC has recently become one of the most lethal cancers in women worldwide. E3 ubiquitin ligases play an important role… read more here.
Keywords: canonical wnt; via activation; expression; pdzrn3 ... See more keywords