Activation of canonical BMP4-SMAD7 signaling suppresses breast cancer metastasis.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer research"
DOI: 10.1158/0008-5472.can-19-0743
Abstract: Metastasis is the major cause of death in cancer patients; with no therapeutic cure, treatments remain largely palliative. As such, new targets and therapeutic strategies are urgently required. Here we show that bone morphogenetic protein-4… read more here.
Keywords: metastasis; smad7; cancer; breast cancer ... See more keywords
Early Socialization Triggered ROS-Mediated Activation of Canonical NF-κB Pathway Leading to Inflammation of Spleen in Suckling Piglets
Sign Up to like & getrecommendations! Published in 2024 at "Agriculture"
DOI: 10.3390/agriculture14070992
Abstract: Early socialization during lactation is advocated as a feeding strategy to reduce the weaning stress of piglets. However, early socialization has often been accompanied by more frequent aggression between individuals, and its effect on the… read more here.
Keywords: early socialization; activation canonical; socialization; canonical pathway ... See more keywords
Lower expression of PDZRN3 induces endometrial carcinoma progression via the activation of canonical Wnt signaling.
Sign Up to like & getrecommendations! Published in 2022 at "Oncology letters"
DOI: 10.3892/ol.2022.13218
Abstract: Endometrial carcinoma (EC) exhibits an extremely malignant biological behavior and has a high mortality rate. EC has recently become one of the most lethal cancers in women worldwide. E3 ubiquitin ligases play an important role… read more here.
Keywords: canonical wnt; via activation; expression; pdzrn3 ... See more keywords