Structural and Thermodynamic Model for the Activation of Cardiac Troponin.
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DOI: 10.1021/acs.biochem.2c00084
Abstract: Cardiac troponin is a regulatory protein complex located on the sarcomere that regulates the engagement of myosin on actin filaments. Low-molecular weight modulators of troponin that bind allosterically with the calcium ion have the potential… read more here.
Keywords: thermodynamic model; activation cardiac; structural thermodynamic; troponin ... See more keywords
Limb-Bud and Heart (LBH) Upregulation in Cardiomyocytes under Hypoxia Promotes the Activation of Cardiac Fibroblasts via Exosome Secretion
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DOI: 10.1155/2022/8939449
Abstract: The activation of cardiac fibroblasts (CFs) after myocardial infarction (MI) is essential for post-MI infarct healing, during which the regulation of transforming growth factor beta1 (TGF-β1) signaling is predominant. We have demonstrated that TGF-β1-mediated upregulation… read more here.
Keywords: via exosome; lbh upregulation; cardiac fibroblasts; lbh ... See more keywords