Cellular mechanism for herbal medicine Junchoto to facilitate intestinal Cl−/water secretion that involves cAMP-dependent activation of CFTR
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DOI: 10.1007/s11418-018-1207-9
Abstract: Constipation is a common symptom frequently compromising the quality of daily life. Several mechanistically different drugs have been used to mitigate constipation, including Japanese herbal (Kampo) medicines. However, the mechanisms of their actions are often… read more here.
Keywords: medicine; water secretion; caco cells; activation cftr ... See more keywords
Allicin Facilitates Airway Surface Liquid Hydration by Activation of CFTR
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DOI: 10.3389/fphar.2022.890284
Abstract: Airway epithelium plays critical roles in regulating airway surface liquid (ASL), the alteration of which causes mucus stasis symptoms. Allicin is a compound released from garlic and harbors the capacity of lung-protection. However, the potential… read more here.
Keywords: activation cftr; cftr; airway epithelium; surface liquid ... See more keywords