CD200Fc limits dendritic cell and B cell activation during chronic allergen exposures.
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DOI: 10.1093/jleuko/qiad042
Abstract: Allergic asthma is a chronic inflammatory disease characterized by Th2, conventional dendritic cell (cDC), and B cell activation. In addition to excessive inflammation, asthma pathogenesis includes dysregulation of anti-inflammatory pathways, such as the CD200/CD200R pathway.… read more here.
Keywords: cell; cdc; dendritic cell; cell activation ... See more keywords
Inflammasome Activation in Chronic Glomerular Diseases.
Sign Up to like & getrecommendations! Published in 2017 at "Current drug targets"
DOI: 10.2174/1389450117666160817103435
Abstract: BACKGROUND The intracellular multiprotein complex termed the inflammasome functions as a platform of pro-inflammatory cytokine production such as IL-1β and IL-18. Under certain conditions, however, the inflammasome produces non-canonical effects such as induction of cell… read more here.
Keywords: activation chronic; inflammasome activation; activation; nlrp3 inflammasome ... See more keywords