Spinal astrocytic c‐Jun N‐terminal kinase (JNK) activation as counteracting mechanism to the amitriptyline analgesic efficacy in painful peripheral neuropathies
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DOI: 10.1016/j.ejphar.2017.01.025
Abstract: ABSTRACT Several drugs and agents are currently used for the treatment of neuropathic pain. Among them amitriptyline, a tricyclic antidepressant drug, represent a first line treatment. Despite its well‐documented clinical efficacy, amitriptyline is ineffective in… read more here.
Keywords: jnk activation; jnk; activation counteracting; efficacy ... See more keywords