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   Articles with "activation domain" as a keyword



Backbone 1H, 13C, and 15N NMR resonance assignments of the Krüppel-like factor 4 activation domain

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recommendations! Published in 2017 at "Biomolecular NMR Assignments"

DOI: 10.1007/s12104-017-9727-x

Abstract: Krüppel-like factor 4 (KLF4) is a transcription factor involved in diverse biological processes, including development, cellular differentiation and proliferation, and maintenance of tissue homeostasis. KLF4 has also been associated with disease states, such as cardiovascular… read more here.

Keywords: ppel like; like factor; activation domain; activation ... See more keywords

A High-Throughput Mutational Scan of an Intrinsically Disordered Acidic Transcriptional Activation Domain.

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recommendations! Published in 2018 at "Cell systems"

DOI: 10.1016/j.cels.2018.01.015

Abstract: Transcriptional activation domains are essential for gene regulation, but their intrinsic disorder and low primary sequence conservation have made it difficult to identify the amino acid composition features that underlie their activity. Here, we describe… read more here.

Keywords: activation domain; high throughput; activation; transcriptional activation ... See more keywords

The 9aaTAD Is Exclusive Activation Domain in Gal4

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recommendations! Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0169261

Abstract: The Gal4 protein is a well-known prototypic acidic activator that has multiple activation domains. We have previously identified a new activation domain called the nine amino acid transactivation domain (9aaTAD) in Gal4 protein. The family… read more here.

Keywords: activation domain; domain gal4; activation; domain 9aatad ... See more keywords

In silico characterization of the interaction of AKR1B1 with the deacetylase activation domain (DAD)

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recommendations! Published in 2025 at "Frontiers in Molecular Biosciences"

DOI: 10.3389/fmolb.2025.1562206

Abstract: The aldo-keto reductase family 1 member B1 (AKR1B1) plays a key role in cancer progression by competing with histone deacetylase 3 to bind to the deacetylase activation domain (DAD) of the nuclear receptor corepressor SMRT.… read more here.

Keywords: dad; domain dad; activation domain; interaction ... See more keywords