A High-Throughput Screen for Transcription Activation Domains Reveals Their Sequence Features and Permits Prediction by Deep Learning.
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DOI: 10.1016/j.molcel.2020.04.020
Abstract: Acidic transcription activation domains (ADs) are encoded by a wide range of seemingly unrelated amino acid sequences, making it difficult to recognize features that promote their dynamic behavior, "fuzzy" interactions, and target specificity. We screened… read more here.
Keywords: transcription; activation domains; transcription activation; acidic ads ... See more keywords