VersicanV1 promotes proliferation and metastasis of hepatocellular carcinoma through the activation of EGFR–PI3K–AKT pathway
Sign Up to like & getrecommendations! Published in 2019 at "Oncogene"
DOI: 10.1038/s41388-019-1052-7
Abstract: Versican has been reported to participate in carcinogenesis in several malignant tumors. However, the accurate role of VersicanV1, a predominant isoform of Versican in liver, remains an enigma in hepatocellular carcinoma (HCC). The expression of… read more here.
Keywords: egfr pi3k; hcc; activation egfr; pi3k akt ... See more keywords
Activation of the EGFR/MAPK pathway drives transdifferentiation of quiescent niche cells to stem cells in the Drosophila testis niche
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.70810
Abstract: Adult stem cells are maintained in niches, specialized microenvironments that regulate their self-renewal and differentiation. In the adult Drosophila testis stem cell niche, somatic hub cells produce signals that regulate adjacent germline stem cells (GSCs)… read more here.
Keywords: drosophila testis; stem cells; hub cells; niche ... See more keywords