Amide activation: an emerging tool for chemoselective synthesis.
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DOI: 10.1039/c8cs00335a
Abstract: It is textbook knowledge that carboxamides benefit from increased stabilisation of the electrophilic carbonyl carbon when compared to other carbonyl and carboxyl derivatives. This results in a considerably reduced reactivity towards nucleophiles. Accordingly, a perception… read more here.
Keywords: tool chemoselective; amide activation; activation; emerging tool ... See more keywords