REST Inhibits Direct Reprogramming of Pancreatic Exocrine to Endocrine Cells by Preventing PDX1-Mediated Activation of Endocrine Genes.
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DOI: 10.1016/j.celrep.2020.107591
Abstract: The emerging appreciation of plasticity among pancreatic lineages has created interest in harnessing cellular reprogramming for β cell replacement therapy of diabetes. Current reprogramming methodologies are inefficient, largely because of a limited understanding of the… read more here.
Keywords: endocrine genes; endocrine; reprogramming pancreatic; pdx1 ... See more keywords