Cholesterol inhibits assembly and oncogenic activation of the EphA2 receptor
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DOI: 10.1038/s42003-025-07786-6
Abstract: The receptor tyrosine kinase EphA2 drives cancer malignancy by facilitating metastasis. EphA2 can be found in different self-assembly states: as a monomer, dimer, and oligomer. However, we have a poor understanding regarding which EphA2 state… read more here.
Keywords: receptor; cholesterol; epha2; activation epha2 ... See more keywords