A rare subset of primary tumor cells with concomitant hyper-activation of extracellular matrix remodeling and dsRNA-IFN1 signaling metastasizes in breast cancer.
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DOI: 10.1158/0008-5472.can-22-2717
Abstract: Metastatic breast cancer (BC) has a poor prognosis and is largely considered incurable. A better understanding of the molecular determinants of BC metastasis could facilitate development of improved prevention and treatment strategies. We used lentiviral… read more here.
Keywords: activation extracellular; concomitant hyper; extracellular matrix; hyper activation ... See more keywords