Substrate delivery mechanism and the role of membrane curvature in factor X activation by extrinsic tenase.
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DOI: 10.1016/j.jtbi.2017.09.015
Abstract: Membrane-bound enzyme complex of extrinsic tenase (VIIa/TF) is believed to be the primary activator of blood clotting in vivo. This complex (where factor VIIa (FVIIa) is a catalytically active part and tissue factor (TF) is… read more here.
Keywords: substrate delivery; tenase; activation extrinsic; extrinsic tenase ... See more keywords
P146 Latent activation of the extrinsic coagulation pathway in patients with ulcerative colitis
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DOI: 10.1093/ecco-jcc/jjad212.0276
Abstract: Ulcerative colitis (UC) is associated with an increased risk of venous thromboembolism. We investigated the correlation of UC severity with latent activation of the extrinsic coagulation pathway and colonic stromal tissue factor (TF) expression. Plasma… read more here.
Keywords: extrinsic coagulation; activation extrinsic; coagulation pathway; culture ... See more keywords