Articles with "activation hepatic" as a keyword



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Knockdown of TRIM15 inhibits the activation of hepatic stellate cells.

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Published in 2021 at "Journal of molecular histology"

DOI: 10.1007/s10735-021-09997-7

Abstract: Liver fibrosis is a global public health problem, and the activation of hepatic stellate cells (HSCs) is the main driving force for liver fibrosis. However, the activation mechanism of HSCs is still not fully understood.… read more here.

Keywords: knockdown trim15; activation hepatic; activation; hepatic stellate ... See more keywords
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Slit2 signaling contributes to cholestatic fibrosis in mice by activation of hepatic stellate cells.

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Published in 2019 at "Experimental cell research"

DOI: 10.1016/j.yexcr.2019.111626

Abstract: Liver Cholestasis is a widespread disease of broad etiologies and ultimately results in fibrosis, which is still lacking effective therapeutic strategies. Activation of hepatic stellate cells (HSCs) is the key event of liver fibrosis. Here,… read more here.

Keywords: fibrosis; stellate cells; activation hepatic; hepatic stellate ... See more keywords

miR‐193a/b‐3p relieves hepatic fibrosis and restrains proliferation and activation of hepatic stellate cells

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Published in 2019 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.14210

Abstract: MicroRNAs (miRNAs) have been confirmed to participate in liver fibrosis progression and activation of hepatic stellate cells (HSCs). In this study, the role of miR‐193a/b‐3p in concanavalin A (ConA)‐induced liver fibrosis in mice was evaluated.… read more here.

Keywords: mir 193a; fibrosis; activation hepatic; liver fibrosis ... See more keywords
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Procyanidin B2 inhibits the activation of hepatic stellate cells and angiogenesis via the Hedgehog pathway during liver fibrosis

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Published in 2019 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.14543

Abstract: Liver fibrosis is a wound‐healing process of liver featured by the over‐deposition of extracellular matrix (ECM) and angiogenesis. However, the effective treatment is lacking. Procyanidin B2 (PB2) is a flavonoid extract abundant in grape seeds… read more here.

Keywords: fibrosis; angiogenesis; liver fibrosis; activation hepatic ... See more keywords