Articles with "activation hepatotoxicity" as a keyword



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In Vitro and In Vivo Metabolic Activation and Hepatotoxicity of Environmental Pollutant 2,6-Dimethylphenol.

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Published in 2022 at "Chemical research in toxicology"

DOI: 10.1021/acs.chemrestox.2c00048

Abstract: 2,6-Dimethylphenol (2,6-DMP) is an environmental pollutant found in industrial wastewater. Exposure to 2,6-DMP is of increasing concern as it endangered reportedly some aquatic animals. In this study, we investigated the metabolic activation and hepatotoxicity of… read more here.

Keywords: vitro vivo; environmental pollutant; metabolic activation; hepatotoxicity ... See more keywords
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Metabolic Activation and Hepatotoxicity of Furan-Containing Compounds

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Published in 2022 at "Drug Metabolism and Disposition"

DOI: 10.1124/dmd.121.000458

Abstract: Furan-containing compounds are abundant in nature, and many, but not all, have been found to be hepatotoxic and carcinogenic. The furan ring present in the chemical structures may be one of the domineering factors to… read more here.

Keywords: furan containing; metabolic activation; hepatotoxicity furan; containing compounds ... See more keywords