Structural Basis of the Activation of Heterotrimeric Gs-Protein by Isoproterenol-Bound β1-Adrenergic Receptor.
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DOI: 10.1016/j.molcel.2020.08.001
Abstract: Cardiac disease remains the leading cause of morbidity and mortality worldwide. The β1-adrenergic receptor (β1-AR) is a major regulator of cardiac functions and is downregulated in the majority of heart failure cases. A key physiological… read more here.
Keywords: adrenergic receptor; heterotrimeric protein; activation; activation heterotrimeric ... See more keywords