Direct activation of HSF1 by macromolecular crowding and misfolded proteins
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DOI: 10.1371/journal.pone.0312524
Abstract: Stress responses play a vital role in cellular survival against environmental challenges, often exploited by cancer cells to proliferate, counteract genomic instability, and resist therapeutic stress. Heat shock factor protein 1 (HSF1), a central transcription… read more here.
Keywords: activation hsf1; stress; hsf1; protein ... See more keywords