Apoptotic Body-Mediated Intracellular Delivery Strategy for Enhanced STING Activation and Improved Tumor Immunogenicity.
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DOI: 10.1021/acs.nanolett.1c03996
Abstract: Agonists of stimulators of interferon genes (STING) are a promising class of immunotherapeutics that trigger potent innate immunity. However, the therapeutic efficacy of conventional STING agonists, such as 2',3'-cyclic guanosine monophosphate-adenosine monophosphate (cGAMP), is severely… read more here.
Keywords: activation improved; enhanced sting; improved tumor; sting activation ... See more keywords