Activation-induced cytidine deaminase: in sickness and in health
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-020-03348-x
Abstract: Activation Induced cytidine Deaminase (AID) is an essential enzyme of the adaptive immune system. Its canonical activity is restricted to B lymphocytes, playing an essential role in the diversification of antibodies by enhancing specificity and… read more here.
Keywords: activation induced; aid; induced cytidine; cytidine deaminase ... See more keywords
Persulfate activation induced by ascorbic acid for efficient organic pollutants oxidation
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2019.122355
Abstract: Abstract In this study, we demonstrate that ascorbic acid (AA) exhibited extremely high activity on persulfate (PS) activation (AA/PS) to produce SO4 − and OH for the degradation of various organic pollutants, including atrazine, pentachlorophenol,… read more here.
Keywords: activation; activation induced; ascorbic acid; oxidation ... See more keywords
HomA and HomB, outer membrane proteins of Helicobacter pylori down-regulate activation-induced cytidine deaminase (AID) and Ig switch germline transcription and thereby affect class switch recombination (CSR) of Ig genes in human B-cells.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular immunology"
DOI: 10.1016/j.molimm.2021.12.014
Abstract: H. pylori is one of the major causes of chronic gastritis, peptic ulcer disease (PUD), gastric mucosa-associated lymphoid tissue lymphoma (MALT) and gastric carcinoma. H. pylori toxin VacA is responsible for host cell apoptosis, whereas… read more here.
Keywords: deaminase aid; switch; activation induced; aid ... See more keywords
NKILA lncRNA promotes tumor immune evasion by sensitizing T cells to activation-induced cell death
Sign Up to like & getrecommendations! Published in 2018 at "Nature Immunology"
DOI: 10.1038/s41590-018-0207-y
Abstract: Activation-induced cell death (AICD) of T lymphocytes can be exploited by cancers to escape immunological destruction. We demonstrated that tumor-specific cytotoxic T lymphocytes (CTLs) and type 1 helper T (TH1) cells, rather than type 2… read more here.
Keywords: cell; activation induced; induced cell; cell death ... See more keywords
Modulation of water diffusion by activation-induced neural cell swelling in Aplysia Californica
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-05586-5
Abstract: Diffusion functional magnetic resonance imaging (DfMRI) has been proposed as a method for functional neuroimaging studies, as an alternative to blood oxygenation level dependent (BOLD)-fMRI. DfMRI is thought to more directly reflect neural activation, but… read more here.
Keywords: diffusion; neural cell; microscopy; activation induced ... See more keywords
Effect of 50-Hz magnetic fields on the expression of activation-induced deaminase, B-cell lymphoma 6 and serum levels of interleukin-6, interleukin-21.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of radiation biology"
DOI: 10.1080/09553002.2023.2177767
Abstract: Background: Investigations showed different effects of magnetic fields (MFs) on the immune system. During humoral immune responses, genes of activation-induced deaminase (AID) and B-cell lymphoma-6 (Bcl-6) are expressed and interleukin (IL)-6 and IL-21 are produced.… read more here.
Keywords: cell lymphoma; serum levels; induced deaminase; expression ... See more keywords
Activation-induced substrate engagement in ERK signaling
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e19-07-0355
Abstract: The extracellular signal-regulated kinase (ERK) pathway is an essential component of developmental signaling in metazoans. Previous models of pathway activation suggested that dissociation of activated dually phosphorylated ERK (dpERK) from MAPK/ERK kinase (MEK), a kinase… read more here.
Keywords: cic; activation induced; induced substrate; erk ... See more keywords
Involvement of activation induced cytidine deaminase in malignant B-cells expressing two distinct M-components as an etiology of biclonal gammopathy
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000032260
Abstract: Biclonal gammopathy (BG) is a rare phenomenon in which 2 M proteins are detected in the same patient, with 2 major hypotheses regarding its etiology. One potential explanation is that completely different malignant B-cell clones… read more here.
Keywords: induced cytidine; etiology; biclonal gammopathy; activation induced ... See more keywords
T cell activation induced marker assays in health and disease.
Sign Up to like & getrecommendations! Published in 2023 at "Immunology and cell biology"
DOI: 10.1111/imcb.12636
Abstract: Activation induced marker (AIM) assays have proven to be an accessible and rapid means of antigen-specific T cell detection. The method typically involves short-term incubation of whole blood or peripheral blood mononuclear cells with antigens… read more here.
Keywords: cell; aim assays; induced marker; cell activation ... See more keywords
Abstract A49: Induction of the lymphomagenic enzyme activation-induced cytidine deaminase (AID) upon in vitro exposure to phenylurea herbicides
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Prevention Research"
DOI: 10.1158/1940-6215.envcaprev19-a49
Abstract: Many studies have drawn associations between pesticide exposures and lymphomagenesis, both in occupational settings and in the general population. The specific compounds responsible for an increased risk of non-Hodgkin lymphoma in pesticide-exposed individuals have not… read more here.
Keywords: activation induced; aid; phenylurea herbicides; induced cytidine ... See more keywords
Platelet heterogeneity in activation-induced glycoprotein shedding: functional effects.
Sign Up to like & getrecommendations! Published in 2018 at "Blood advances"
DOI: 10.1182/bloodadvances.2017011544
Abstract: The platelet receptors glycoprotein Ibα (GPIbα) and GPVI are known to be cleaved by members of a disintegrin and metalloprotease (ADAM) family (ADAM10 and ADAM17), but the mechanisms and consequences of this shedding are not… read more here.
Keywords: glycoprotein shedding; activation induced; heterogeneity activation; activation ... See more keywords