PAR1 activation induces rapid changes in glutamate uptake and astrocyte morphology
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DOI: 10.1038/srep43606
Abstract: The G-protein coupled, protease-activated receptor 1 (PAR1) is a membrane protein expressed in astrocytes. Fine astrocytic processes are in tight contact with neurons and blood vessels and shape excitatory synaptic transmission due to their abundant… read more here.
Keywords: glutamate uptake; induces rapid; par1 activation; activation ... See more keywords
Maternal immune activation induces methylation changes in schizophrenia genes
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DOI: 10.1371/journal.pone.0278155
Abstract: Susceptibility to schizophrenia is mediated by genetic and environmental risk factors. Infection driven maternal immune activation (MIA) during pregnancy is a key environmental risk factor. However, little is known about how MIA during pregnancy could… read more here.
Keywords: methylation changes; maternal immune; activation induces; schizophrenia ... See more keywords
Prolonged Piezo1 Activation Induces Cardiac Arrhythmia
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DOI: 10.3390/ijms24076720
Abstract: The rhythmical nature of the cardiovascular system constantly generates dynamic mechanical forces. At the centre of this system is the heart, which must detect these changes and adjust its performance accordingly. Mechanoelectric feedback provides a… read more here.
Keywords: cardiac arrhythmias; piezo1 activation; mechanoelectric feedback; prolonged piezo1 ... See more keywords