Articles with "activation irf5" as a keyword



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Microbial recognition by GEF-H1 controls IKKε mediated activation of IRF5

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Published in 2019 at "Nature Communications"

DOI: 10.1038/s41467-019-09283-x

Abstract: During infection, transcription factor interferon regulatory factor 5 (IRF5) is essential for the control of host defense. Here we show that the microtubule-associated guanine nucleotide exchange factor (GEF)-H1, is required for the phosphorylation of IRF5… read more here.

Keywords: irf5; gef; recognition; activation irf5 ... See more keywords