Minocycline inhibits sleep deprivation-induced aberrant microglial activation and Keap1-Nrf2 expression in mouse hippocampus
Sign Up to like & getrecommendations! Published in 2021 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2021.05.028
Abstract: Sleep deprivation (SD) is a hallmark of modern society and associated with many neuropsychiatric disorders, including depression and anxiety. However, the cellular and molecular mechanisms underlying SD-associated depression and anxiety remain elusive. Does the neuroinflammation… read more here.
Keywords: minocycline; sleep deprivation; activation keap1; keap1 nrf2 ... See more keywords
7-deacetylgedunin suppresses inflammatory responses through activation of Keap1/Nrf2/HO-1 signaling
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DOI: 10.18632/oncotarget.19017
Abstract: Macrophages play a critical role in a variety of inflammatory diseases. Activation of Keap1/Nrf2/HO-1 signaling results in inactivation of macrophages and amelioration of inflammatory and autoimmune conditions. Hence, discovery for the activators of Keap1/Nrf2/HO-1 signaling… read more here.
Keywords: activation keap1; keap1 nrf2; nrf2 signaling; deacetylgedunin ... See more keywords