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Published in 2018 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.02445-17
Abstract: ABSTRACT When overproduced, the multidrug efflux system MexEF-OprN increases the resistance of Pseudomonas aeruginosa to fluoroquinolones, chloramphenicol, and trimethoprim. In this work, we demonstrate that gain-of-function mutations in the regulatory gene mexT result in oligomerization…
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Keywords:
pseudomonas aeruginosa;
activation mext;
constitutive activation;
clinical isolates ... See more keywords