Activation of mGlu2/3 receptors, a novel therapeutic approach to alleviate dyskinesia and psychosis in experimental parkinsonism
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DOI: 10.1016/j.neuropharm.2019.107725
Abstract: Selective blockade of serotonin 2A (5-HT2A) receptors is a promising strategy to reduce L-3,4-dihydroxyphenylalanine (l-DOPA)-induced dyskinesia and has shown efficacy in a Phase III clinical trial for dopaminergic psychosis in Parkinson's disease (PD). However, pre-clinical… read more here.
Keywords: mglu2 receptors; activation mglu2; dyskinesia psychosis; mglu2 ... See more keywords