Transcriptional activation of the MICA gene with an engineered CRISPR-Cas9 system.
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DOI: 10.1016/j.bbrc.2017.03.076
Abstract: Major histocompatibility complex class I polypeptide-related sequence A (MICA) is a prototypical NKG2D ligand. Because immune cells, such as natural killer (NK) cells, recognize virally infected or transformed cells and eliminate them through the interaction… read more here.
Keywords: activation mica; mica; mica gene; transcriptional activation ... See more keywords