Mitohormesis in Mice via Sustained Basal Activation of Mitochondrial and Antioxidant Signaling.
Sign Up to like & getrecommendations! Published in 2018 at "Cell metabolism"
DOI: 10.1016/j.cmet.2018.07.011
Abstract: Transient mitochondrial stress can promote beneficial physiological responses and longevity, termed "mitohormesis." To interrogate mitohormetic pathways in mammals, we generated mice in which mitochondrial superoxide dismutase 2 (SOD2) can be knocked down in an inducible… read more here.
Keywords: mitochondrial antioxidant; mitohormesis; activation mitochondrial; antioxidant signaling ... See more keywords
Activation of mitochondrial unfolded protein response protects against multiple exogenous stressors
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DOI: 10.26508/lsa.202101182
Abstract: This work highlights the importance of the mitochondrial unfolded protein response in allowing organisms to survive external stressors through up-regulation of other stress response pathways. read more here.
Keywords: response; unfolded protein; protein response; activation mitochondrial ... See more keywords
PS-NPs Induced Neurotoxic Effects in SHSY-5Y Cells via Autophagy Activation and Mitochondrial Dysfunction
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DOI: 10.3390/brainsci12070952
Abstract: Polystyrene nanoparticles (PS-NPs) are organic pollutants that are widely detected in the environment and organisms, posing potential threats to both ecosystems and human health. PS-NPs have been proven to penetrate the blood–brain barrier and increase… read more here.
Keywords: via autophagy; activation mitochondrial; autophagy activation; shsy cells ... See more keywords