Rationally Designed Molecules Synergistically Modulate Multifaceted Aβ Toxicity, Microglial Activation, and Neuroinflammation.
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DOI: 10.1021/acschemneuro.2c00276
Abstract: Synergistic modulation of multifaceted toxicity is the key to tackle multifactorial Alzheimer's disease (AD). The etiology of AD includes amyloid β (Aβ) amyloidosis, metal ion dyshomeostasis, reactive oxygen species (ROS), oxidative stress, mitochondrial damage, and… read more here.
Keywords: rationally designed; microglial activation; toxicity; activation neuroinflammation ... See more keywords